Thomas Midgley Jr. was responsible for two of the most environmentally damaging inventions of the 20th century. An environmental historian said he “had more impact on the atmosphere than any other single organism in Earth’s history.”
Midgley apparently got lead poisoning himself, and was moved to the refrigeration division, where he was part of the team that developed freon. It went into fridges, and later was used in spray cans as a propellant. Freon was the very first CFC; so we can add ozone depletion and a “super” greenhouse gas to his roster.
Midgley’s inventions ended up killing him as well: disabled by polio, he set up a system of ropes and pulleys to move in and out of bed. At 51 years old, he got tangled up in the ropes and died.
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